Treatment for high risk early-stage breast cancer is transforming, with CDK4/6 inhibitor data extending survival. We explore the management of patients in this setting with Jenny Gilchrist, Nurse Practitioner in Breast Oncology at Macquarie University Hospital, Samantha Moules, McGrath Breast Care Nurse, Genesis Care Northern Sydney and Michael Fitzgerald, Nurse Practitioner – Medical Oncology Cancer Services at Flinders Medical Centre in Adelaide. This podcast is available to CNSA Members. To listen to the full podcast, log into the membership portal.